1-alpha-hydroxycholecalciferol for renal osteodystrophy.
نویسندگان
چکیده
منابع مشابه
Whole-body in-vivo neutron activation analysis in assessing treatment of renal osteodystrophy with 1-alpha-hydroxycholecalciferol.
Four selected adults with different patterns of osteodystrophy receiving regular dialysis were treated with 1-alpha-hydroxycholecalciferol (1-alpha-OHD3) 0-5-2 mug/day for 10 to 12 months. In two patients, one with osteitis fibrosa and the other with osteomalacia, significant biochemical, radiological, and histological improvements occurred, and total body calcium measured by in-vivo neutron ac...
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Previous studies from this laboratory demonstrated that secondary hyperparathyroidism in dogs with chronic renal disease may occur, at least in part, as a consequence of the need for progressive adaptation in renal phosphorus (P) excretion that occurs as glomerular filtration rate falls. However, the studies were of relatively short duration. Moreover, no information emerged regarding a potenti...
متن کاملRenal osteodystrophy.
The incidence of chronic renal disease is increasing, and the pattern of renal osteodystrophy seems to be shifting from the classic hyperparathyroid presentation to one of low bone turnover. Patients with persistent disease also live longer than previously and are more physically active. Thus, patients may experience trauma as a direct result of increased physical activity in a setting of weake...
متن کاملEffect of 1-alpha-hydroxycholecalciferol on magnesium metabolism in chronic renal failure.
Effect of 1-alpha-hydroxycholecalciferol on magnesium metabolism in chronic renal failure Vitamin D derivatives and analogues are increasingly being used to treat bone disease in chronic renal failure but their effects on magnesium metabolism have not been fully documented. The use of 1-oc-hydroxycholecalciferol (1-m-OHDD) in chronic renal failure, however, may be associated with a special risk...
متن کاملEffect of low dose 1 alpha-hydroxycholecalciferol on glomerular filtration rate in moderate renal failure.
Serial measurements of 51Cr edetic acid clearance were made over a period of one year in two groups of 8 children, in a double blind trial of 1 alpha-hydroxycholecalciferol (10 ng/kg/day) and calciferol (670 ng/kg/day). Glomerular filtration rate (GFR) at the beginning of the trial was 20-50 ml/min/1.73 m2; it rose in the children given 1 alpha-hydroxycholecalciferol (group A) after 6 months bu...
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ژورنال
عنوان ژورنال: BMJ
سال: 1977
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.6089.721